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Simparica Trio 22.1-44 lbs Dogs, 6 Month Supply

SKU#:

95108

Protects dogs against heartworm disease, ticks & fleas, roundworms & hookworms

Regular Price:Crossed Out$206.74Your Price:$165.40
E PAW Price:  $148.85

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This product requires a prescription

1. We’ll ask for your vet’s info during checkout.

2. We’ll verify your prescription and ship your order.

Details and state availability.

Simparica Trio (sarolaner, moxidectin, and pyrantel chewable tablets)

is a flavored, chewable tablet for administration to dogs 8 weeks of age and older.

Simparica Trio for dogs is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina) and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections.

Simparica Trio kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations with Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black?legged tick), and Rhipicephalus sanguineus (brown dog tick) for one month in dogs and puppies 8 weeks of age and older, and weighing 2.8 pounds or greater.

We proudly ensure that our products are obtained directly from the manufacturer or their authorized distributor, guaranteeing their authenticity and backed by the manufacturer themselves.

See all Simparica Trio Dosages

Our pharmacists are available for counseling regarding prescriptions purchased from PetPawsRx before and after dispensing. Monday - Friday, 9 AM - 2 PM CST. 1-800-367-4444.

Customer Reviews

Based on 8 reviews
Rating
  • Linda L.
    Verified Buyer

    Great price!

    Best price anywhere. Very fast shipping!

    Published date
    03/13/26
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  • Elizabeth D.
    Verified Buyer

    Best Price Around

    PetPawsRx saves me over $80 a box on this medication, and their customer service in assisting me ordering it is fantastic. They are a lifeline!

    Published date
    01/15/26
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  • Troy S.
    Verified Buyer

    More info about the rewards program

    Want to know all details of reward program before automatically entering customers into it

    Published date
    12/14/25
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  • Erica F.
    Verified Buyer

    Great price

    PetPawsRX has the best prices on Simparica Trio. The purchase and shipping process is always easy and fast.

    Published date
    12/12/25
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  • Marie H.
    Verified Buyer

    Wonderful service

    I ordered the Simparica Trio second 6 month supply over the phone and within a few days the pet meds arrived! Wonderful service from this company and great prices. Thank you for your timely delivery.

    Published date
    12/08/25
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  • Richard W.
    Verified Buyer

    Great service, product I needed

    Great service from this company. They even called me to tell me I had to mail in the script as my vet didn’t take phone calls scripts. Shipped quickly after they received it. I’ve been using them for a couple of years now

    Published date
    11/11/25
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  • Phyllis H.
    Verified Buyer

    GREAT!

    This was a great purchase. However, it did not let me choose the lbs on the order so the vet had to adjust it.

    Published date
    10/09/25
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  • Rebecca R.
    Verified Reviewer

    All-in-one chewable

    I love that this product reduces the need for multiple medications. No more liquid vials that leave a residue on my dogs coat. This chewable tablet prevents heartworm and provides flea and tick protection all in one! Also, PetPaws offers the best price and fast shipping.

    Published date
    09/22/25
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