NexGard Plus vs. NexGard

Flea and tick prevention often becomes part of a familiar routine, yet small differences between medications can carry long-term implications for a dog’s health. Some treatments focus strictly on external parasites, while others extend protection beyond what’s visible. That distinction can raise questions when it’s time to choose. For many pet owners, comparing nexgard plus vs nexgard becomes a practical step toward feeling more confident in that decision.

Both NexGard and NexGard Plus are monthly chewable medications designed to protect dogs from parasites. They come in soft, beef-flavored chews that most dogs accept easily and are available by prescription. While they share a similar format, the level of protection they cover is where they begin to differ.

NexGard is a monthly chew that protects dogs against fleas and ticks using the active ingredient afoxolaner. It focuses on external parasite control and is commonly used for routine flea and tick prevention.

NexGard Plus is also a monthly chew, but it combines flea and tick protection with heartworm prevention and treatment of intestinal parasites. Its added ingredients expand coverage beyond external parasites, making it a more comprehensive option.

Both NexGard and NexGard Plus are given once every 30 days to maintain consistent protection. Staying on schedule matters, as gaps between doses can leave dogs exposed to parasites that are harder to manage once established.

Many pet owners find it helpful to set a reminder or align dosing with a recurring date each month. Keeping a steady routine supports ongoing protection and helps reduce the risk of missed doses.

Both medications are generally safe when used as directed, though it’s still helpful to know what to watch for.

• NexGard is commonly used for flea and tick protection, but may not be ideal for dogs with a history of seizures, as it belongs to the isoxazoline class.
• NexGard Plus adds heartworm prevention and intestinal parasite treatment. Dogs should be tested for heartworms before starting, since it’s intended for prevention.

Mild side effects like upset stomach or low energy are uncommon. Rarely, neurological reactions or allergic responses can occur. If anything seems unusual, contacting a veterinarian is recommended.

The right choice depends on the level of protection a dog needs.

NexGard works well for flea and tick coverage. NexGard Plus may be a better fit when heartworm and intestinal parasites are also a concern.

With the right routine in place, staying consistent becomes easier. For added convenience and savings, Sign up and Save! Subscribe to our Newsletter.